Comparison of the clinical efficacy of subcutaneous vs. oral administration of methotrexate in patients with psoriasis vulgaris: a randomized controlled trial.

Chareon Choonhakarn Suteeraporn Chaowattanapanit Narachai JulanonPanita Limpawattana

Published in: Clinical and experimental dermatology (2022)

SC and oral administration of MTX had similar efficacies in improving the PASI score even at the highest tolerable dose; however, the SC MTX group had higher overall patient satisfaction than the oral MTX group. No difference in tolerability was found.

Keyphrases

patient satisfaction
open label
high dose
randomized controlled trial
clinical trial
double blind