Estrogen as a guardian of auditory health: Tsp1-CD47 axis regulation and noise-induced hearing loss.

Xiaoxue Wang H Zheng B Yang M ZuZ WangJ Zhang F ZhengM YangMichael Chi-Fai Tong L Zhao Wen-Pei Bai

Published in: Climacteric : the journal of the International Menopause Society (2023)

OVX rats were more susceptible to NIHL, and the protective effect of estrogen was achieved through regulation of the Tsp1-CD47 axis. This study presents a novel mechanism through which estrogen regulates NIHL and offers a potential intervention strategy for the clinical treatment of NIHL.

Keyphrases

hearing loss
estrogen receptor
randomized controlled trial
healthcare
public health
high glucose
mental health
nk cells
human health
air pollution
working memory
drug induced
health information
risk assessment
endothelial cells