Characterization of the Clinical Significance of PD-1/PD-Ls Expression and Methylation in Patients With Low-Grade Glioma.

Jie MeiYun CaiRui XuXuejing YangWeijian ZhouHuiyu WangChaoying Liu

Published in: Technology in cancer research & treatment (2021)

To conclude, overexpression and hypo-methylation of PD-1/PD-Ls predicted unfavorable prognosis in LGG patients, suggesting those patients may benefit from PD1/PD-Ls checkpoint inhibitors treatment.

Keyphrases

end stage renal disease
low grade
ejection fraction
newly diagnosed
chronic kidney disease
dna methylation
prognostic factors
peritoneal dialysis
dna damage
poor prognosis
high grade
genome wide
oxidative stress
patient reported
long non coding rna
combination therapy