Dysregulation of PLOD2 Promotes Tumor Metastasis and Invasion in Hepatocellular Carcinoma.
Keren LiYi NiuKai LiChengrui ZhongZhiyu QiuYichuan YuanYunxing ShiZhu LinZhenkun HuangDinglan ZuoYichuan YuanBin-Kui LiPublished in: Journal of clinical and translational hepatology (2023)
High expression of PLOD2 was regulated by IRF5, which was correlated with the poor survival of HCC patients. PLOD2 enhanced HCC metastasis via BIRC3, suggesting that PLOD2 might be a valuable prognostic biomarker for HCC treatment.