Symptom clusters for revising scale membership in the analysis of prostate cancer patient reported outcome measures: a secondary data analysis of the Medical Research Council RT01 trial (ISCRTN47772397).

Agnieszka LemanskaTao ChenDavid P DearnaleyRajesh JenaMatthew R SydesSara Faithfull

Published in: Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation (2017)

This study adds to the knowledge on how cluster analysis can be applied for the interpretation and utilisation of PROMs. We conclude that multiple-item scales should be evaluated and that symptom clusters provide a study-specific approach for modelling and interpretation of PROMs.

Keyphrases

patient reported
patient reported outcomes
prostate cancer
healthcare
radical prostatectomy
study protocol
electronic health record
randomized controlled trial
phase iii
big data
data analysis
open label