The manufacturing of 3D-printed microfluidic chips to analyse the effect upon particle size during the synthesis of lipid nanoparticles.
Edward WeaverEssyrose MathewJay CaldwellAndrew HookerShahid UddinDimitrios A LamprouPublished in: The Journal of pharmacy and pharmacology (2022)
The influence of total flow rates and lipid choice is investigated in depth, to provide further clarification on how a microfluidic setup should be optimised. In-depth explanations of the importance of each channel parameter are also explained throughout, with reference to their importance for the properties of a successful liposome.