Longitudinal Branched-Chain Amino Acids, Lifestyle Intervention, and Type 2 Diabetes in the Finnish Diabetes Prevention Study.

Jemina Kivelä Jelena MeiniläMatti UusitupaJaakko TuomilehtoJaana Lindström

Published in: The Journal of clinical endocrinology and metabolism (2022)

Lifestyle intervention modified the association of the baseline BCAA concentration and BCAA trajectories with the incidence of T2D. Our study adds to the accumulating evidence on the mechanisms behind the effect of lifestyle changes on the risk of T2D.

Keyphrases

type diabetes
cardiovascular disease
metabolic syndrome
randomized controlled trial
physical activity
weight loss
glycemic control
depressive symptoms
risk factors
adipose tissue
skeletal muscle