Increased serum concentration of netrin-1 after intravitreal bevacizumab injection: is it a compensatory mechanism to counteract drug side effects?

Murat Okutucu Huseyin Findik Mehmet Gökhan Aslan Medeni Arpa

Published in: BMC ophthalmology (2021)

Intravitreal BCZ injections work systemically to significantly decrease serum VEGF levels, leading to a significant upregulation in the concentration of another angiogenic mediator, netrin-1.

Keyphrases

vascular endothelial growth factor
diabetic retinopathy
age related macular degeneration
ultrasound guided
endothelial cells
poor prognosis
emergency department
signaling pathway
metastatic colorectal cancer