MarZIC: A Marginal Mediation Model for Zero-Inflated Compositional Mediators with Applications to Microbiome Data.
Quran WuJames O'MalleySusmita DattaRaad Z GharaibehChristian JobinMargaret R KaragasModupe O CokerAnne G HoenBrock C ChristensenJuliette C MadanZhigang LiPublished in: Genes (2022)
When analyzing the zero-inflated microbiome composition as the mediators, MarZIC approach has better performance than standard causal mediation analysis approaches and existing competing approach.