MarZIC: A Marginal Mediation Model for Zero-Inflated Compositional Mediators with Applications to Microbiome Data.

Quran WuJames O'MalleySusmita DattaRaad Z GharaibehChristian JobinMargaret R KaragasModupe O CokerAnne G HoenBrock C ChristensenJuliette C MadanZhigang Li

Published in: Genes (2022)

When analyzing the zero-inflated microbiome composition as the mediators, MarZIC approach has better performance than standard causal mediation analysis approaches and existing competing approach.

Keyphrases

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