TAS-303 effects on urethral sphincter function in women with stress urinary incontinence: phase I study.
Makoto YonoShin IrieMomokazu GotohPublished in: International urogynecology journal (2020)
No significant difference in MUCP and urethral closure pressure was found between TAS-303 and placebo. However, the change in the proximal urethral closure pressure with TAS-303 was larger than that with placebo. This suggests that TAS-303 has pharmacological effects on urethral sphincteric function.