New Composite Contrast Agents Based on Ln and Graphene Matrix for Multi-Energy Computed Tomography.
Evgeniya V SuslovaAlexei P KozlovDenis A ShashurinVladislav A RozhkovRostislav V SotenskiiSergei V MaximovSerguei V SavilovOleg S MedvedevGeorgy A ChelkovPublished in: Nanomaterials (Basel, Switzerland) (2022)
The subject of the current research study is aimed at the development of novel types of contrast agents (CAs) for multi-energy computed tomography (CT) based on Ln-graphene composites, which include Ln (Ln = La, Nd, and Gd) nanoparticles with a size of 2-3 nm, acting as key contrasting elements, and graphene nanoflakes (GNFs) acting as the matrix. The synthesis and surface modifications of the GNFs and the properties of the new CAs are presented herein. The samples have had their characteristics determined using X-ray photoelectron spectroscopy, X-Ray diffraction, transmission electron microscopy, thermogravimetric analysis, and Raman spectroscopy. Multi-energy CT images of the La-, Nd-, and Gd-based CAs demonstrating their visualization and discriminative properties, as well as the possibility of a quantitative analysis, are presented.
Keyphrases
- dual energy
- computed tomography
- electron microscopy
- contrast enhanced
- crispr cas
- image quality
- genome editing
- raman spectroscopy
- positron emission tomography
- magnetic resonance imaging
- magnetic resonance
- walled carbon nanotubes
- high resolution
- deep learning
- carbon nanotubes
- optical coherence tomography
- photodynamic therapy
- mass spectrometry