Specific Gait Changes in Prodromal Hereditary Spastic Paraplegia Type 4: preSPG4 Study.
Christian LaßmannWinfried IlgMarc SchneiderMaximilian VölkerDaniel F B HaeufleRebecca SchüleMartin A GieseMatthis SynofzikLudger SchölsTim W RattayPublished in: Movement disorders : official journal of the Movement Disorder Society (2022)
Gait analysis can quantify changes in prodromal and mild-to-moderate manifest SPG4 patients. Thus, gait features constitute promising motor biomarkers characterizing the subclinical progression of spastic gait and might help to evaluate interventions in early disease stages. © 2022 The Authors. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.