Prevalence of multimorbidity and its impact on survival in people with motor neuron disease.
Stella A GlasmacherPatrick K A KearnsJuan LarrazLucy StirlandArpan R MehtaJudith NewtonChristopher J WeirSiddharthan ChandranSuvankar Palnull nullPublished in: European journal of neurology (2021)
Multimorbidity is common in MND, necessitating holistic interdisciplinary management, but age is the dominant predictor of prognosis in people with MND. Excluding people with MND and multimorbidity from trial participation may do little to homogenise the cohort in terms of survival potential and could harm generalisability.