[Biomarkers of neuroinflammation in patients with chronic cerebral ischemia during the therapy with vinpocetine (study INFLAMARK)].

I N Samartsev S A Zhivolupov O V Gorbatenkova V V Ponomarev J S Butakova

Published in: Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova (2023)

The use of vinpocetine can significantly reduce the severity of cognitive and affective disorders, asthenia, normalize the circadian rhythm of sleep, suppress the expression S100β and IL-1β in patients with CCI. One of the vinpocetine's mechanisms of action may be the inhibition of neuroinflammation.

Keyphrases

cerebral ischemia
subarachnoid hemorrhage
brain injury
blood brain barrier
poor prognosis
traumatic brain injury
neuropathic pain
lipopolysaccharide induced
bipolar disorder
physical activity
lps induced
cognitive impairment
heart rate
blood pressure
binding protein
bone marrow
smoking cessation
replacement therapy