Randomized Study on Dose Escalation in Definitive Chemoradiation for Patients With Locally Advanced Esophageal Cancer (ARTDECO Study).
Maarten C C M HulshofElisabeth D GeijsenTom RozemaVera OppedijkJeroen BuijsenKaren J NeelisJoost J M E NuyttensMaurice J C van der SangenPaul M JeeneJannie G ReindersMark Ivo van Berge HenegouwenAdriana ThanoJeanin E van HooftHanneke W M van LaarhovenAte van der GaastPublished in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2021)
In dCRT for esophageal cancer, radiation dose escalation up to 61.6 Gy to the primary tumor did not result in a significant increase in local control over 50.4 Gy. The absence of a dose effect was observed in both AC and SCC.