Krüppel-like Factor (KLF) family members control expression of genes required for serous cavity and alveolar macrophage identities.

Kathleen PestalLeianna C SlaydenGregory M Barton

Published in: bioRxiv : the preprint server for biology (2024)

Previous studies have identified many specific regulators of macrophage development. This work reveals the requirement of members of the Group 2 KLF transcription factor family in the determination of the identity of distinct tissue-resident macrophages.

Keyphrases

transcription factor
genome wide identification
adipose tissue
dna binding
poor prognosis
high grade
patient safety
genome wide
quality improvement
binding protein
bioinformatics analysis
dna methylation
emergency medicine