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Analyzing of colorectal cancerrelated genes and microRNAs expression profiles in response to probiotics Lactobacillus acidophilus and Saccharomyces cerevisiae in colon cancer cell lines.

Kosar Naderi SaffarMohaddeseh LarypoorMaryam Bikhof Torbati
Published in: Molecular biology reports (2024)
The findings of this study indicate that probiotics can effectively suppress the proliferation of colorectal cancer cells and even reverse their development. Additionally, the study of cellular genes and miRNA profiles associated with colorectal cancer have demonstrated that our probiotics play a crucial role in CRC prevention by increasing the expression of tumor suppressor microRNAs and their target genes while decreasing oncogenes.
Keyphrases
  • saccharomyces cerevisiae
  • genome wide
  • poor prognosis
  • genome wide identification
  • gene expression
  • bioinformatics analysis
  • dna methylation