Pain sensitivities predict prophylactic treatment outcomes of flunarizine in chronic migraine patients: A prospective study.
Li-Ling Hope PanYen-Feng WangYu-Hsiang LingKuan-Lin LaiShih-Pin ChenWei-Ta ChenRolf-Detlef TreedeShuu-Jiun WangPublished in: Cephalalgia : an international journal of headache (2022)
Chronic migraine were generally more sensitive compared to healthy controls. Preventive treatment with flunarizine should be recommended particularly for chronic migraine who have relatively normal sensitivity to mechanical punctate or heat pain.Trial registration: This study was registered on ClinicalTrials.gov (Identifier: NCT02747940).