Effect of Protein Supplementation on Plasma Sodium Levels in the Syndrome of Inappropriate Antidiuresis - a Monocentric Open-Label Proof-of-Concept Study - the TREASURE Study.
Sophie MonneratCihan AtilaFabienne BaurJoyce Santos de JesusJulie C RefardtMichael DickenmannMirjam Christ-CrainPublished in: European journal of endocrinology (2023)
Our findings suggest that protein supplementation with protein powder increases plasma sodium levels in patients with chronic SIAD through protein-induced ureagenesis and osmotic diuresis. The effects are comparable to oral urea intake.