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Umami taste receptor suppresses cancer cachexia by regulating skeletal muscle atrophy in vivo and in vitro .

Sumin LeeYoonha ChoiYerin KimYeon Kyung ChaTai Hyun ParkYuri Kim
Published in: Nutrition research and practice (2024)
Taken together, the umami taste receptor exerts protective effects on muscle-wasting conditions by restoring dysregulated muscle atrophy in cancer cachexia. In conclusion, this result provided evidence that the umami taste receptor exerts a therapeutic anti-cancer cachexia effect by restoring muscle atrophy.
Keyphrases
  • skeletal muscle
  • papillary thyroid
  • squamous cell
  • insulin resistance
  • signaling pathway
  • type diabetes
  • squamous cell carcinoma
  • lymph node metastasis
  • young adults