Oxytocin in young children with Prader-Willi syndrome: Results of a randomized, double-blind, placebo-controlled, crossover trial investigating 3 months of oxytocin.
Layla DamenLionne N GrootjenAlicia F JuriaansStephany H DonzeT Martin HuismanJenny A VisserPatric J D DelhantyAnita C S Hokken-KoelegaPublished in: Clinical endocrinology (2020)
Intranasal oxytocin treatment has positive effects on social and eating behaviour in 3-11 years aged boys with PWS and in children with a deletion without safety concerns. Intranasal oxytocin in children with PWS might be considered, but individual effects should be carefully evaluated and treatment discontinued if no effects are found.