Ferritin heavy/light chain (FTH1/FTL) expression, serum ferritin levels, and their functional as well as prognostic roles in acute myeloid leukemia.

Sarah BertoliEtienne PaubelleEmilie BérardEstelle SalandXavier G ThomasSuzanne TavitianMarie-Virginie LarcherFrançois VergezEric DelabesseAudrey SarryFrançoise HuguetClément LarrueClaudie BoscThomas FargeJean Emmanuel SarryMauricette MichalletChristian Recher

Published in: European journal of haematology (2018)

Ferritin is deregulated in most AML patients likely through inflammation, associated with chemoresistance, and could represent a new therapeutic target.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
poor prognosis
oxidative stress
acute myeloid leukemia
peritoneal dialysis
prognostic factors
long non coding rna