Placental expression of ENG, VEGF, and FLT: Gender-specific associations with maternal vitamin B12 status.

C ManiP KochharG RavikumarP DwarkanathC N SheelaS GeorgeA ThomasJ CrastaTinku ThomasA V KurpadPratibha Dwarkanath

Published in: European journal of clinical nutrition (2019)

Maternal trimester 1 vitamin B12 status was associated negatively with placental ENG and VEGF expression predominantly in the female births. Therefore, we hypothesize that the placenta adapts to low maternal vitamin B12 status by up-regulating angiogenic pathways in a gender-specific manner.

Keyphrases

pregnancy outcomes
birth weight
poor prognosis
gestational age
vascular endothelial growth factor
endothelial cells
acute myeloid leukemia
mental health
binding protein
pregnant women
preterm birth
long non coding rna
tyrosine kinase
physical activity