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Asthma and decreased lung function in children exposed to perfluoroalkyl and polyfluoroalkyl substances (PFAS): An updated meta-analysis unveiling research gaps.

Ata RafieeSasan FaridiPeter D SlyLara StoneLynsey P KennedyE Melinda Mahabee-Gittens
Published in: Environmental research (2024)
Our findings suggest that children who are exposed to PFOA are at a higher risk of developing asthma as well as the association between exposure to PFOS with impaired lung function. Large longitudinal studies with homogeneous PFAS exposures and standardized outcome measures are needed to ascertain these outcomes with improved certainty as well as toxicological studies to investigate the underlying mechanisms.
Keyphrases
  • lung function
  • air pollution
  • chronic obstructive pulmonary disease
  • cystic fibrosis
  • case control
  • systematic review
  • young adults
  • randomized controlled trial
  • meta analyses
  • adipose tissue