Circulating cathelicidin levels correlate with mucosal disease activity in ulcerative colitis, risk of intestinal stricture in Crohn's disease, and clinical prognosis in inflammatory bowel disease.
Diana Hoang-Ngoc TranJiani WangChristina HaWendy HoS Anjani MattaiAngelos OikonomopoulosGuy WeissPrecious LaceyMichelle ChengChristine ShiehCaroline C MussattoSamantha HoDaniel HommesHon Wai KoonPublished in: BMC gastroenterology (2017)
Co-evaluation of LL-37 and CRP can indicate mucosal disease activity in UC patients. LL-37 can predict future clinical activity in IBD patients and indicate risk of intestinal stricture in CD patients.