Testosterone use in postmenopausal women.
A MartinezSusan R DavisPublished in: Climacteric : the journal of the International Menopause Society (2020)
The physiological, clinical and therapeutic aspects of testosterone in women's health are still a matter of controversy and debate. Quality evidence data of clinical trials favors the use of transdermal testosterone in postmenopausal women with female sexual dysfunction causing distress. Doses of testosterone should approximate physiological testosterone levels found in premenopausal women, avoiding supraphysiological concentrations that expose women to adverse events. Short-term treatment periods have been shown to be effective and safe in postmenopausal women with hypoactive sexual desire disorder/dysfunction. However, long-term safety of testosterone use must be determined.
Keyphrases
- replacement therapy
- postmenopausal women
- bone mineral density
- breast cancer risk
- polycystic ovary syndrome
- clinical trial
- mental health
- smoking cessation
- healthcare
- pregnancy outcomes
- public health
- oxidative stress
- adipose tissue
- pregnant women
- randomized controlled trial
- artificial intelligence
- type diabetes
- insulin resistance
- metabolic syndrome
- quality improvement
- body composition
- big data
- combination therapy
- climate change
- social media
- deep learning
- data analysis