Effect of ferric citrate on hippocampal iron accumulation and widespread molecular alterations associated with cognitive disorder in an ovariectomized mice model.
Lingling CuiHuijun ZhouYudan HaoXiaoli YangZhiqian LiYuting GaoZhengya ZhangLina RenLinpu JiRuijie SunYibo WangXian WangPublished in: CNS neuroscience & therapeutics (2024)
Iron exposure could cause histopathological damage in the hippocampus of ovariectomised mice and, by altering hippocampal proteomics, particularly the expression of hippocampal iron metabolism-related proteins, could further influence cognitive impairment in ovariectomized mice.