Proteomic Characterization of Circulating Molecular Perturbations Associated With Pancreatic Adenocarcinoma Following Intravenous ω-3 Fatty Acid and Gemcitabine Administration: A Pilot Study.
Franscois RunauAli ArshadJohn D IsherwoodJatinderpal K SandhuLeong L NgAshley R DennisonDonald J L JonesPublished in: JPEN. Journal of parenteral and enteral nutrition (2020)
This pilot study demonstrates administration of ω-3FA has potential anti-inflammatory, antiangiogenic, and proapoptotic effects via direct interaction with cancer-signaling pathways in patients with advanced pancreatic adenocarcinoma. Further studies in a larger sample size is required to validate the clinical correlation found in this preliminary study.