Reducing the Damage of Ox-LDL/LOX-1 Pathway to Vascular Endothelial Barrier Can Inhibit Atherosclerosis.
Xiaopeng GuoYishan GuoZhiwen WangBingxin CaoChuangsheng ZhengZhuanglin ZengYumiao WeiPublished in: Oxidative medicine and cellular longevity (2022)
An Ox-ApoB-PF antibody may protect the endothelial cell physiological function and survival status by blocking the combination of Ox-LDL/LOX-1 in vascular endothelial cells. Immune intervention with Ox-ApoB-PF inhibits the occurrence and development of atherosclerotic lesions by protecting the vascular endothelial barrier function.