Deciphering the Clinical Behaviour of Invasive Lobular Carcinoma of the Breast Defines an Aggressive Subtype.

Shorouk MakhloufNehal M AtallahSusanna PolottoAndrew H S LeeAndrew R GreenEmad A Rakha

Published in: Cancers (2024)

pILC and high-grade sILC variants comprise an aggressive ILC subtype associated with poor prognostic characteristics and a poor response to chemotherapy. These results warrant confirmation in randomised clinical trials.

Keyphrases

clinical trial
high grade
open label
low grade
double blind
phase ii
study protocol
locally advanced
randomized controlled trial
squamous cell carcinoma
radiation therapy