Incorporation of CAD (computer-aided detection) with thin-slice lung CT in routine 18F-FDG PET/CT imaging read-out protocol for detection of lung nodules.
Ujwal BhureMatthäus CiecieraDirk LehnickMaria Del Sol Pérez LagoHannes GrünigThiago LimaJustus E RoosKlaus StrobelPublished in: European journal of hybrid imaging (2023)
Implementation of CAD for the detection of lung nodules/metastases in routine 18F-FDG PET/CT read-out is feasible. The combination of diagnostic thin-slice CT and CAD significantly increases the detection rate of lung nodules in tumor patients compared to the standard PET/CT read-out. PET combined with low-dose CT showed the best balance between sensitivity and specificity regarding the diagnosis of metastases per patient. CAD reduces the time required for lung nodule/metastasis detection, especially for less experienced readers.
Keyphrases
- pet ct
- loop mediated isothermal amplification
- coronary artery disease
- low dose
- image quality
- computed tomography
- positron emission tomography
- real time pcr
- healthcare
- randomized controlled trial
- single molecule
- primary care
- dual energy
- newly diagnosed
- high resolution
- clinical practice
- prognostic factors
- fluorescence imaging