Outcomes of Implementing in the Real World the Women's Health CoOp Intervention in Cape Town, South Africa.
Wendee M WechsbergFelicia A BrowneJacqueline NdiranguCourtney Peasant BonnerTracy L KlineMargaret GichaneWilliam A ZulePublished in: AIDS and behavior (2021)
Women in South Africa living with HIV who use alcohol may not adhere to ART, affecting the country's 90-90-90 targets. The Women's Health CoOp (WHC), a woman-focused HIV intervention, has shown efficacy in numerous trials with key populations of women in South Africa who use alcohol and drugs. In a hybrid implementation effectiveness study, the WHC was implemented in usual care clinics by healthcare providers in a modified stepped-wedge design. We present the outcomes of alcohol use and ART adherence with 480 women, with a 95% 6-month follow-up rate across 4 implementation cycles. Compared with the first cycle, women in the fourth cycle were significantly less likely (OR = 0.10 [95% CI 0.04, 0.24]) to report alcohol use disorder risk and were 4 times more likely (OR = 4.16 [95% CI 1.05, 16.51]) to report ART adherence at 6-month follow-up. Overall, acceptability and satisfaction were extremely high. The WHC intervention was successful in reaching key populations of women to reduce alcohol use and increase ART adherence, which is essential for South Africa to reach the 90-90-90 goals.
Keyphrases
- south africa
- healthcare
- polycystic ovary syndrome
- hiv positive
- randomized controlled trial
- antiretroviral therapy
- pregnancy outcomes
- hiv infected
- primary care
- breast cancer risk
- public health
- cervical cancer screening
- quality improvement
- health information
- mental health
- palliative care
- hepatitis c virus
- clinical trial
- adipose tissue
- insulin resistance
- study protocol
- hiv aids
- metabolic syndrome
- pregnant women
- skeletal muscle
- men who have sex with men