Dynamic glucose-enhanced (DGE) MRI in the human brain at 7 T with reduced motion-induced artifacts based on quantitative R1ρ mapping.

Philip S Boyd Johannes BreitlingFerdinand ZimmermannAndreas Korzowski Moritz Zaiss Patrick SchuenkeNina WeinfurtnerHeinz-Peter SchlemmerMark E LaddPeter BachertDaniel Paech Steffen Goerke

Published in: Magnetic resonance in medicine (2019)

The presented 3D acquisition protocol enables DGE-MRI examinations in the human brain with improved robustness against motion-induced artifacts. Correction of motion-induced artifacts is of high importance for DGE-MRI in clinical studies where an unambiguous assignment of contrast changes due to an actual change in local glucose concentration is a prerequisite.

Keyphrases

contrast enhanced
high glucose
diabetic rats
magnetic resonance imaging
drug induced
randomized controlled trial
diffusion weighted imaging
oxidative stress
endothelial cells
high speed
adipose tissue
metabolic syndrome
blood pressure