PDZ Proteins SCRIB and DLG1 Regulate Myeloma Cell Surface CD86 Expression, Growth, and Survival.

Tyler Moser-KatzCatherine M GavileBenjamin G BarwickKelvin P LeeLawrence H Boise

Published in: Molecular cancer research : MCR (2022)

These findings demonstrate the importance of proper trafficking of CD86 to the cell surface in myeloma cell survival and may provide a new therapeutic target in this disease.

Keyphrases

cell surface
multiple myeloma
poor prognosis
newly diagnosed
nk cells
binding protein
free survival