Exendin-4 Improves Diabetic Kidney Disease in C57BL/6 Mice Independent of Brown Adipose Tissue Activation.

Shu Fang Yingying Cai Fuping Lyu Hongbin Zhang Chunyan Wu Yanmei Zeng Cunxia FanShaozhou ZouYudan ZhangPing LiLing Wang Yao-Ming Xue Mei-Ping Guan

Published in: Journal of diabetes research (2020)

Exendin-4 could decrease the renal lipid deposit and improve diabetic nephropathy via activating the renal AMPK pathway independent of BAT activation.

Keyphrases

diabetic nephropathy
adipose tissue
type diabetes
signaling pathway
insulin resistance
high fat diet
high fat diet induced
fatty acid
metabolic syndrome
protein kinase