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Prophylactic treatment of rapamycin ameliorates naturally developing and episode -induced heterotopic ossification in mice expressing human mutant ACVR1.

Hirotsugu MaekawaShunsuke KawaiMegumi NishioSanae NagataYonghui JinHiroyuki YoshitomiShuichi MatsudaJunya Toguchida
Published in: Orphanet journal of rare diseases (2020)
Our study suggested that prophylactic treatment will be a choice of method for the clinical application of rapamycin for FOP.
Keyphrases
  • endothelial cells
  • high glucose
  • mouse model
  • wild type
  • combination therapy
  • diabetic rats
  • decision making
  • smoking cessation
  • pluripotent stem cells