Circulating plasma microRNA profiling in patients with polymyositis/dermatomyositis before and after treatment: miRNA may be associated with polymyositis/dermatomyositis.
Takuya HiraiKeigo IkedaHiroshi TsushimaMaki FujishiroKunihiro HayakawaYuko YoshidaShinji MorimotoKen YamajiYoshinari TakasakiKenji TakamoriNaoto TamuraIwao SekigawaPublished in: Inflammation and regeneration (2018)
This is the first report describing plasma miRNA expression profiles in PM/DM patients. The present data suggest that plasma levels of miRNAs may be associated with polymyositis/dermatomyositis and hsa-miR-4442 could be used as a biomarker for PM/DM diagnosis and/or disease activity.
Keyphrases
- interstitial lung disease
- disease activity
- rheumatoid arthritis
- systemic sclerosis
- systemic lupus erythematosus
- rheumatoid arthritis patients
- idiopathic pulmonary fibrosis
- end stage renal disease
- ankylosing spondylitis
- particulate matter
- air pollution
- chronic kidney disease
- juvenile idiopathic arthritis
- ejection fraction
- newly diagnosed
- cell proliferation
- heavy metals
- peritoneal dialysis
- prognostic factors
- polycyclic aromatic hydrocarbons
- single cell
- electronic health record
- patient reported outcomes
- insulin resistance
- water soluble
- risk assessment
- deep learning
- patient reported
- artificial intelligence
- weight loss