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Intensive treatment of hyperglycemia in the acute phase of myocardial infarction: the tenuous balance between effectiveness and safety - a systematic review and meta-analysis of randomized clinical trials.

Paulo H NegreirosAdriana A BauWilson Nadruz JuniorOtávio Rizzi Coelho-FilhoJosé Roberto Matos SouzaOtavio R CoelhoAndrei Carvalho SpositoLuiz Sérgio Fernandes de Carvalho
Published in: Revista da Associacao Medica Brasileira (1992) (2019)
This meta-analysis suggests that there may be a tenuous line between the effectiveness and safety of reducing blood glucose in the acute phase of MI. The targets must not exceed a reduction greater than 36 mg/dL in relation to estimated average blood glucose.
Keyphrases
  • blood glucose
  • systematic review
  • glycemic control
  • blood pressure
  • heart failure
  • meta analyses
  • left ventricular
  • randomized controlled trial
  • adipose tissue
  • replacement therapy
  • skeletal muscle
  • weight loss