Methotrexate as a corticosteroid-sparing agent in leprosy reactions: A French multicenter retrospective study.

Léa JaumeEstelle HauGentiane MonselAntoine MahéAntoine BertolottiAntoine PetitBritney LeMarie ChauveauElisabeth DuhamelThierry MaisonobeMartine BagotJean-David BouazizFaïza MougariEmmanuelle CambauMarie Jachietnull null

Published in: PLoS neglected tropical diseases (2023)

MTX seems to be an effective alternative treatment in LRs, allowing for GCs-sparing with a good safety profile. Furthermore, early introduction during LRs may lead to a better therapeutic response. However, its efficacy seems to suggest prolonged therapy to prevent recurrence.

Keyphrases

robot assisted
high dose
cross sectional
stem cells
free survival
cell therapy