Loss of microRNA-30a and sex-specific effects on the neonatal hyperoxic lung injury.

Sandra L GrimmSamuel ReddickXiaoyu DongConnor LeekAmy Xiao WangManuel Cantu GutierrezSean M HartigBhagavatula MoorthyCristian CoarfaKrithika Lingappan

Published in: Biology of sex differences (2023)

miR-30a could be one of the biological factors mediating the resilience of the female preterm lung to neonatal hyperoxic lung injury. A better understanding of the effects of miR-30a on pulmonary angiogenesis and alveolarization may lead to novel therapeutics for treating BPD.

Keyphrases

cell proliferation
long non coding rna
long noncoding rna
pulmonary hypertension
endothelial cells
small molecule
climate change
preterm birth
social support
vascular endothelial growth factor
gestational age
depressive symptoms