Shedding light on cashmere goat hair follicle biology: from morphology analyses to transcriptomic landascape.
Cristina NocelliKatia CappelliStefano CapomaccioLuisa PascucciFrancesca MercatiIrene PazzagliaSamanta MecocciMarco AntoniniCarlo RenieriPublished in: BMC genomics (2020)
As in the isolated hair follicles, some target genes were homogenously modulated during the four hair follicle phases. Ceruloplasmin (CP) and Keratin 4 (K4), confirmed their clear cut expression between growing and resting phase. In fact, K4 was almost absent in catagen phases while CP was barely expressed in anagen phases. In particular, the strong expression of K4 in early anagen makes it an eligible marker to track the beginning of a new hair cycle, and therefore defining the optimum time for cashmere harvesting.