Biodistribution and radiation dose estimates for 68Ga-DOTA-JR11 in patients with metastatic neuroendocrine tumors.

Simone KrebsNeeta Pandit-TaskarDiane ReidyBradley J BeattieSerge K LyashchenkoJason S LewisLisa BodeiWolfgang A WeberJoseph A O'Donoghue

Published in: European journal of nuclear medicine and molecular imaging (2018)

68Ga-DOTA-JR11 demonstrated rapid tumor uptake, high tumor/background ratios, and rapid clearance from blood. The low liver background is advantageous and may facilitate detection of liver metastases. Dosimetric data compare favorably with published data for 68Ga-DOTATATE and 68Ga-DOTATOC.

Keyphrases

pet ct
loop mediated isothermal amplification
liver metastases
neuroendocrine tumors
positron emission tomography
electronic health record
radiation therapy
randomized controlled trial
machine learning
computed tomography