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Early introduction of peanut reduces peanut allergy across risk groups in pooled and causal inference analyses.

Kirsty LoganHenry T BahnsonAlyssa YlescupidezKirsten BeyerJohanna BellachDianne E CampbellJoanna CravenGeorge Du ToitE N MillsMichael R PerkinGraham C RobertsRonald van ReeGideon Lack
Published in: Allergy (2022)
We demonstrate a significant reduction in PA with early peanut introduction in a large group of pooled, randomized participants. This significant reduction was demonstrated across all risk subgroups, including children with no eczema. Furthermore, our results point to increased efficacy of the intervention with earlier age of introduction.
Keyphrases
  • phase iii
  • randomized controlled trial
  • double blind
  • young adults
  • open label
  • atopic dermatitis
  • placebo controlled
  • clinical trial
  • phase ii
  • study protocol