Metabolic Pathway Analysis and Effectiveness of Tamoxifen in Danish Breast Cancer Patients.

Thomas P AhernLindsay J CollinJames W BaurleyAnders KjærsgaardRebecca NashMaret L MaliniakPer Damkier Michael E ZwickR Benjamin IsettPeer M Christiansen Bent EjlertsenKristina L LauridsenKristina B Christensen Rebecca A SillimanHenrik T SørensenTrine TrammStephen Jacques Hamilton-DutoitTimothy L LashDeirdre Cronin-Fenton

Published in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology (2020)

These results are consistent with guidelines recommending against genotype-guided prescribing of tamoxifen, and for the first time provide evidence supporting these guidelines in premenopausal women.

Keyphrases

clinical practice
breast cancer cells
estrogen receptor
primary care
positive breast cancer
randomized controlled trial
polycystic ovary syndrome
systematic review
postmenopausal women
breast cancer risk
pregnancy outcomes
type diabetes
emergency department
pregnant women
metabolic syndrome
drug induced