The effectiveness of ocriplasmin versus surgery for the treatment of macular holes: A systematic review and meta-analysis.
Brian Edward YuTom SheidowRaman-Deep Singh SambhiPhil HooperMonali S Malvankar-MehtaPublished in: European journal of ophthalmology (2020)
Results suggested 92% macular hole closure after vitrectomy compared to 34% after ocriplasmin. A significant improvement in visual acuity of patients was seen after both treatments. More good quality randomized controlled trials are required to make strong conclusions.
Keyphrases
- diabetic retinopathy
- randomized controlled trial
- end stage renal disease
- optical coherence tomography
- minimally invasive
- ejection fraction
- newly diagnosed
- chronic kidney disease
- systematic review
- peritoneal dialysis
- prognostic factors
- coronary artery bypass
- clinical trial
- age related macular degeneration
- coronary artery disease
- patient reported outcomes
- combination therapy