Histopathologic Oral Cancer Prediction Using Oral Squamous Cell Carcinoma Biopsy Empowered with Transfer Learning.
Atta-Ur RahmanAbdullah AlqahtaniNahier AldhafferiMuhammad Umar NasirMuhammad Farhan KhanMuhammad Adnan KhanAbdolhossein Hemmati-SarapardehPublished in: Sensors (Basel, Switzerland) (2022)
Oral cancer is a dangerous and extensive cancer with a high death ratio. Oral cancer is the most usual cancer in the world, with more than 300,335 deaths every year. The cancerous tumor appears in the neck, oral glands, face, and mouth. To overcome this dangerous cancer, there are many ways to detect like a biopsy, in which small chunks of tissues are taken from the mouth and tested under a secure and hygienic microscope. However, microscope results of tissues to detect oral cancer are not up to the mark, a microscope cannot easily identify the cancerous cells and normal cells. Detection of cancerous cells using microscopic biopsy images helps in allaying and predicting the issues and gives better results if biologically approaches apply accurately for the prediction of cancerous cells, but during the physical examinations microscopic biopsy images for cancer detection there are major chances for human error and mistake. So, with the development of technology deep learning algorithms plays a major role in medical image diagnosing. Deep learning algorithms are efficiently developed to predict breast cancer, oral cancer, lung cancer, or any other type of medical image. In this study, the proposed model of transfer learning model using AlexNet in the convolutional neural network to extract rank features from oral squamous cell carcinoma (OSCC) biopsy images to train the model. Simulation results have shown that the proposed model achieved higher classification accuracy 97.66% and 90.06% of training and testing, respectively.
Keyphrases
- deep learning
- convolutional neural network
- induced apoptosis
- artificial intelligence
- papillary thyroid
- machine learning
- cell cycle arrest
- ultrasound guided
- healthcare
- squamous cell
- endoplasmic reticulum stress
- fine needle aspiration
- oxidative stress
- endothelial cells
- gene expression
- squamous cell carcinoma
- physical activity
- optical coherence tomography
- cell proliferation
- young adults
- signaling pathway
- childhood cancer
- pi k akt
- cell death
- mass spectrometry
- pluripotent stem cells
- anti inflammatory