Efficacy and acceptability of cognitive-behavioral therapy and serotonin reuptake inhibitors for pediatric obsessive-compulsive disorder: a network meta-analysis.
Matti CervinJoseph F McGuireJohann M D'SouzaAlessandro S De NadaiKristina AspvallWayne K GoodmanPer AndrénSophie C SchneiderDaniel A GellerDavid Mataix-ColsEric A StorchPublished in: Journal of child psychology and psychiatry, and allied disciplines (2024)
In-person CBT and SRIs produce clear benefits compared to waitlist and pill placebo and should be integral parts of the clinical management of pediatric OCD, with in-person CBT overall having a stronger evidence base. The combination of in-person CBT and SRIs may be most efficacious, but few studies hinder firm conclusions. The efficacy of CBT appears conserved when delivered via webcam/telephone, while more trials evaluating ICBT are needed.