Long Noncoding RNAs CARMN, LUCAT1, SMILR, and MALAT1 in Thoracic Aortic Aneurysm: Validation of Biomarkers in Clinical Samples.

Vaiva PatamsyteGiedrius ŽukovasDovydas GečysDiana ŽaliaduonytėPovilas JakuškaRimantas BenetisVaiva Lesauskaitė

Published in: Disease markers (2020)

We have shown that the expression of lncRNAs CARMN and LUCAT1 is reduced in dilated aortic tissue and that the LUCAT1 and SMILR expression is lower in the blood plasma of TAA patients. Decreased LUCAT1 expression in TAA patients' blood plasma may have diagnostic potential in discriminating patients with TAA.

Keyphrases

end stage renal disease
poor prognosis
ejection fraction
newly diagnosed
chronic kidney disease
peritoneal dialysis
prognostic factors
heart failure
patient reported outcomes
aortic valve
pulmonary artery
spinal cord injury
pulmonary hypertension
atrial fibrillation