Changes in cerebral cortex activity during a simple motor task after MRgFUS treatment in patients affected by essential tremor and Parkinson's disease: a pilot study using functional NIRS.

To our knowledge, our study is the first that showed the use of fNIRS system to measure the cortical activity changes following unilateral Ventral Intermediate Nucleus (VIM) thalamotomy after MRgFUS treatment. Our findings showed that therapeutic MRgFUS promoted the remodeling of neuronal networks and changes in cortical activity in association with symptomatic improvements.