Montelukast in paediatric asthma and allergic rhinitis: a systematic review and meta-analysis.

Karina Mayoral Catalina Lizano-Barrantes Víctor Zamora Àngels Pont Carme Miret Cristina Barrufet María Araceli Caballero-Rabasco Manuel Praena-Crespo Alberto Bercedo-Sanz Laura Valdesoiro-Navarrete María Teresa Guerra Yolanda Pardo María José Martinez-Zapata Olatz Garin Montserrat Ferrernull null

Published in: European respiratory review : an official journal of the European Respiratory Society (2023)

The synthesis of the available evidence suggests that, in children and adolescents, montelukast was effective in controlling asthma symptoms when compared with placebo, but inhaled corticosteroids were superior in controlling symptoms, especially at night-time. These findings of our systematic review concur with current guidelines for asthma treatment.

Keyphrases

allergic rhinitis
systematic review
chronic obstructive pulmonary disease
lung function
meta analyses
intensive care unit
emergency department
randomized controlled trial
clinical trial
depressive symptoms
double blind
study protocol